MICROFLUIDIC SYNTHESIS OF VINBLASTINE-LOADED MULTIFUNCTIONAL PARTICLES FOR MAGNETICALLY RESPONSIVE CONTROLLED DRUG RELEASE

Microfluidic Synthesis of Vinblastine-Loaded Multifunctional Particles for Magnetically Responsive Controlled Drug Release

Vinblastine (VBL) is a major chemotherapeutic drug; however, in some cases, it may cause severe side effects in patients with cancer.Designing a novel VBL pharmaceutical formulation is a crucial and emerging concern among researchers for reducing the use of VBL.This study developed a stimuli-responsive controlled VBL drug release system from magnet

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Reassessment of Plio-Quaternary aquifer mineralization (Sidi Mansour plain, Southern Tunisia): a machine learning approach

Understanding aquifer mineralization is crucial for sustainable water resource management.Thus, the Plio-Quaternary aquifer of the Sidi Mansour plain was studied in detail for reassessment of its heterogeneous mineralization water.Geochemical analysis and stable (18O, 2H) and radiogenic isotope (3H, 14C) analyses have provided a better understandin

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Health provider and service-user experiences of sensory modulation rooms in an acute inpatient psychiatry setting.

BackgroundSensory modulation rooms (SMRs) are therapeutic spaces that use sensory modulation concepts and strategies to assist service users to self-regulate and modulate arousal levels.SMRs are increasingly being explored as strength-based and person-centered adjuncts to care for people receiving inpatient psychiatry services.The aim of this study

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Exploring the progression of drug dependence in a methamphetamine self-administration rat model through targeted and non-targeted metabolomics analyses

Abstract Persistent neurochemical and biological disturbances resulting from repeated cycles of drug reward, withdrawal, and relapse contribute to drug dependence.Methamphetamine (MA) wavertree and london cosmopolitan candle is a psychostimulant with substantial abuse potential and neurotoxic effects, primarily affecting monoamine neurotransmitter

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Design method of modular bi-directional load-bearing and energy dissipating joints in the context of intelligent construction

The requirements for structural performance and seismic performance in the field of civil engineering are increasing.Traditional building structures have certain limitations in extreme conditions such as earthquakes.Therefore, this ps5 edmonton in stock study discusses the design of modular bi-directional load-bearing and energy dissipating joints

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